Marge Simpson Seth MacFarlance

The longstanding Griffin-Simpsons rivalry will come to a head when Family Guy creator Seth MacFarlane attempts to steal Marge Simpson away from Homer on The Simpsons 25th season premiere next fall.

Entertainment Weekly reports that the episode, “Dangers on a Train,” finds Marge meeting a man named Ben (MacFarlane) on a website for married people looking to have an affair (she mistakes it for a cupcake-baking site) and the pair hit it off. “We wanted to come together in a bipartisan way to make Fox Sunday night rock,” said The Simpsons executive producer Al Jean of the casting. “This was all very fun… There’s been a little rivalry. We’re both humor shows and we make jokes, but it’s always been friendly.”